The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2023
Filed:
Dec. 15, 2020
Applicants:
Tufts Medical Center, Boston, MA (US);
Trustees of Tufts College, Medford, MA (US);
Inventors:
Alan S. Kopin, Wellesley, MA (US);
Krishna Kumar, Cambridge, MA (US);
Jamie Raudensky Doyle, Newton, MA (US);
Assignees:
Tufts Medical Center, Boston, MA (US);
Trustees of Tufts College, Medford, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); A61K 38/33 (2006.01); C07K 7/08 (2006.01); C07K 14/665 (2006.01); C07K 14/68 (2006.01); C07K 19/00 (2006.01); C07K 7/00 (2006.01); A61K 47/54 (2017.01); A61K 47/65 (2017.01); A61K 47/60 (2017.01); A61P 25/00 (2006.01); A61K 38/34 (2006.01); C07K 7/64 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 38/10 (2013.01); A61K 38/33 (2013.01); A61K 38/34 (2013.01); A61K 47/542 (2017.08); A61K 47/60 (2017.08); A61K 47/65 (2017.08); A61P 25/00 (2018.01); C07K 7/00 (2013.01); C07K 7/64 (2013.01); C07K 14/68 (2013.01); C07K 19/00 (2013.01);
Abstract
The present disclosure relates to, among other things, compounds and methods for treating neuropathic pain, ocular pain, ocular inflammation, and/or dry eye and methods of detecting mutations in specific G-protein coupled receptors, such as missense mutations, and determining the extent to which these mutations alter the pharmacological response of the G-protein coupled receptor.