The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2023
Filed:
Oct. 27, 2022
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Jonathan Ostrem, San Francisco, CA (US);
Ulf Peters, San Francisco, CA (US);
Kevan M. Shokat, San Francisco, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61K 38/17 (2006.01); C07D 231/40 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 409/04 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 471/10 (2006.01); C07D 487/10 (2006.01); C07D 207/14 (2006.01); C07D 211/62 (2006.01); C07D 295/185 (2006.01); C07D 295/26 (2006.01); C07D 211/58 (2006.01); C07D 487/04 (2006.01); C12N 9/14 (2006.01); C07C 235/20 (2006.01); C07C 317/08 (2006.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61K 38/1709 (2013.01); C07C 235/20 (2013.01); C07C 317/08 (2013.01); C07D 207/14 (2013.01); C07D 211/58 (2013.01); C07D 211/62 (2013.01); C07D 231/40 (2013.01); C07D 295/185 (2013.01); C07D 295/26 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 409/04 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 471/10 (2013.01); C07D 487/04 (2013.01); C07D 487/10 (2013.01); C12N 9/14 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Y 306/05002 (2013.01); G01N 2500/04 (2013.01);
Abstract
K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.