The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2023
Filed:
Mar. 08, 2021
Lubris Llc, Naples, FL (US);
Rhode Island Hospital, Providence, RI (US);
Gregory D. Jay, Norfolk, MA (US);
Benjamin D. Sullivan, Concord, MA (US);
Tannin Avery Schmidt, Avon, CT (US);
Khaled Elsaid, Irvine, CA (US);
Edward R. Truitt, Medina, WA (US);
Roman Krawetz, Calgary, CA;
Jawed Fareed, Westchester, IL (US);
Joanna Szmydynger-Chodobska, Providence, RI (US);
Adam Chodobski, Providence, RI (US);
Lubris LLC, Naples, FL (US);
Rhode Island Hospital, Providence, RI (US);
Abstract
Disclosed herein are methods of using PRG4 glycoprotein, also known as lubricin, to reduce, inhibit, or down-regulate pro-inflammatory pathways in patients at risk of or suffering from an inflammatory response or allergy symptom through CD44 antagonization, regulating pro-inflammatory cytokine production, inhibiting NF-κB translocation and/or facilitating removal of inflammation-inducing cellular or matrix debris or allergens.