The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2023
Filed:
Mar. 02, 2021
Applicant:
University of Kentucky Research Foundation, Lexington, KY (US);
Inventors:
Jayakrishna Ambati, Lexington, KY (US);
Benjamin Fowler, Lexington, KY (US);
Kameshwari Ambati, Lexington, KY (US);
Assignee:
University of Kentucky Research Foundation, Lexington, KY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61P 25/16 (2018.01); A61P 25/28 (2018.01);
Abstract
The present disclosure relates to compounds and compositions that inhibit the NLRP3 inflammasome, for example, or a pharmaceutically acceptable salt thereof. Also disclosed are methods for treating, and in particular methods for treating macular degeneration, e.g., dry age-related macular degeneration (AMD) and wet AMD, Alzheimer's disease, multiple sclerosis, and Parkinson's disease, using compounds and compositions that inhibit the NLRP3 inflammasome.