The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2023
Filed:
Mar. 15, 2019
Applicants:
Washington University IN St. Louis, St. Louis, MO (US);
New York University, New York, NY (US);
Inventors:
Jennifer A. Philips, St. Louis, MO (US);
Kathryn Moore, New York, NY (US);
Pallavi Chandra, St. Louis, MO (US);
Mireille Ouimet, New York, NY (US);
Assignees:
Washington University in St. Louis, St. Louis, MO (US);
New York University, New York, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/495 (2006.01); A61K 31/336 (2006.01); A61K 45/06 (2006.01); A61K 31/198 (2006.01); A61K 31/352 (2006.01); A61K 31/365 (2006.01); A61K 31/4453 (2006.01); A61K 31/155 (2006.01);
U.S. Cl.
CPC ...
A61K 31/495 (2013.01); A61K 31/198 (2013.01); A61K 31/336 (2013.01); A61K 31/352 (2013.01); A61K 31/365 (2013.01); A61K 31/4453 (2013.01); A61K 31/155 (2013.01); A61K 45/06 (2013.01);
Abstract
Methods of using small molecule inhibitors of fatty acid oxidation (FAO) as antimicrobials against intracellular Mycobacteria are disclosed. FAO inhibitors including etomoxir, trimetazidine, oxfenicine perhexeline and/or can be used alone, or in combination with known as antimycobacterial agents against intracellular Mycobacteria.