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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11716974 B1

PDFFull Text
Date of Patent:
Aug. 08, 2023

Filed:

Jun. 27, 2017

Human liver chimeric mouse with deficient p450 oxidoreductase

Applicant:

Baylor College of Medicine, Houston, TX (US);

Inventors:

Karl-Dimiter Bissig, Houston, TX (US);

Maria de las Mercedes Barzi Dieguez, Houston, TX (US);

Peter Francis Pankowicz, Houston, TX (US);

Assignee:

Baylor College of Medicine, Houston, TX (US);

Attorneys:

Cooley LLP

Matthew Pavao

Primary Examiner:

Anoop K Singh

Int. Cl.
CPC ...
A01K 67/027 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0271 (2013.01); A01K 67/0276 (2013.01); A61K 49/0008 (2013.01); A01K 2207/15 (2013.01); A01K 2217/075 (2013.01); A01K 2217/206 (2013.01);
Abstract

The present disclosure provides a chimeric non-human animal comprising human hepatocytes, methods for preparing the chimeric non-human animal comprising human hepatocytes and methods of utilizing the chimeric non-human animal comprising human hepatocytes to screening and identifying metabolites for any type of drugs, typically small molecule drugs, which might affect human liver functions and any other bodily function.

Find Patent Forward Citations

Bissig, Karl-Dimiter. (2023). Human liver chimeric mouse with deficient p450 oxidoreductase (U.S. Patent No. 11716974). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11716974

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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