The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2023
Filed:
Jul. 04, 2018
Applicants:
Martin Andersson, Mölndal, SE;
Mats Hulander, Gothenburg, SE;
Gustav Sundell, Gothenburg, SE;
Inventors:
Assignee:
Vitroprobe Analytics AB, Gothenburg, SE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 1/36 (2006.01); G01N 23/046 (2018.01); B81B 1/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6803 (2013.01); B81B 1/008 (2013.01); G01N 1/36 (2013.01); G01N 23/046 (2013.01);
Abstract
The present invention relates to a method for determining the three dimensional structure of biomolecules, such as proteins, protein fragments, and peptides. The biomolecule is encapsulated in an amorphous silica matrix, from which a needle specimen is prepared. Atom probe tomography is then used to analyze the needle specimen and the data is used to reconstruct the three dimensional structure of the biomolecule. The present invention greatly facilitates determination of the three dimensional structure of biomolecules.