The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 01, 2023

Filed:

Dec. 13, 2018
Applicant:

Syngenta Participations Ag, Basel, CH;

Inventors:

Michele Yarnell, Research Triangle Park, NC (US);

Anne Chevrel, Nantes, FR;

Olivier Kitten, Nantes, FR;

Scott Young, Research Triangle Park, NC (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); G01N 33/569 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/68 (2013.01); C07K 14/00 (2013.01); G01N 33/56961 (2013.01); G01N 2333/415 (2013.01);
Abstract

The invention relates generally to synthetic non-antibody protein scaffolds (synNAPS) that differentially detect or quantitate a target insecticidal protein in a complex biological matrix comprising the target protein and a non-target insecticidal protein and to methods of using the synNAPS in immunoassays, and more particularly to monoclonal antibodies and immunoassays for the differential detection and quantitation of a wild-type crystal protein, such as a wild-type-Cry1Ab, fromand hybrid crystal proteins, which comprise all or a significant portion of the wild-type Cry protein in complex biological samples comprising both the wild-type Cry protein and one or more of the hybrid Cry proteins.


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