The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2023
Filed:
Jun. 20, 2017
Applicant:
Octapharma Ag, Lachen, CH;
Inventors:
Karina Nawrath, Lachen, CH;
Janine Guendel, Lachen, CH;
Sven Bahrke, Lachen, CH;
Lars Stoeckl, Lachen, CH;
Steffen Goletz, Lachen, CH;
Assignee:
Octapharma AG, Lachen, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 9/22 (2006.01); C12N 9/64 (2006.01); C12N 15/10 (2006.01); C12P 21/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); C12N 9/22 (2013.01); C12N 9/6437 (2013.01); C12N 15/102 (2013.01); C12P 21/005 (2013.01); C12Y 304/21021 (2013.01); C12N 15/1137 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01);
Abstract
The present invention relates to a method of modifying at least one gene in a cell via CRISPR/Cas, wherein the at least one gene has at least three alleles. The present invention further relates to cells obtainable by the method of the invention. Additionally, the present invention provides a method of producing a protein in a cell obtainable by the method of modifying at least one gene of the invention. Moreover, the invention relates to proteins obtainable by the method of producing a protein and use thereof, for example in therapy.