The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 01, 2023

Filed:

Jun. 17, 2020
Applicant:

Deka Products Limited Partnership, Manchester, NH (US);

Inventors:

Richard E. Andrews, Manchester, NH (US);

Stephanie M. Miskell, Weare, NH (US);

Zachary T. Kops, Watertown, MA (US);

Justin M. Ferrentino, Mont Vernon, NH (US);

Michael C. Tilley, Amherst, NH (US);

Andrew K. Capulli, Auburn, NH (US);

Keira L McGrath, Manchester, NH (US);

Stuart A. Jacobson, Lexington, MA (US);

Assignee:

DEKA PRODUCTS LIMITED PARTNERSHIP, Manchester, NH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/36 (2006.01); B01L 3/00 (2006.01); B01L 9/06 (2006.01); C12M 3/06 (2006.01); C12M 1/00 (2006.01); C12M 1/26 (2006.01); C12M 1/12 (2006.01); C12M 1/02 (2006.01); C12M 1/34 (2006.01); G01N 35/00 (2006.01); G01N 35/10 (2006.01);
U.S. Cl.
CPC ...
C12M 41/48 (2013.01); B01L 3/50273 (2013.01); B01L 9/06 (2013.01); C12M 23/16 (2013.01); C12M 29/00 (2013.01); C12M 33/10 (2013.01); C12M 37/00 (2013.01); C12M 41/18 (2013.01); C12M 41/36 (2013.01); C12M 41/44 (2013.01); C12M 45/20 (2013.01); G01N 35/00732 (2013.01); G01N 35/1004 (2013.01); G01N 35/1079 (2013.01); B01L 2300/021 (2013.01); B01L 2300/041 (2013.01); B01L 2300/0609 (2013.01); B01L 2300/1805 (2013.01); B01L 2400/0475 (2013.01); B01L 2400/06 (2013.01);
Abstract

Manufacturing system and method for creating multiple tissue constructs from cells. System can include a thaw subsystem (if the cells are provided in a frozen state), an expansion subsystem, a concentration subsystem, and a tissue maturation subsystem. Each of these subsystems is modular and can be reconfigured, and the process can be repeated depending on the specific tissue process being implemented. Multiple tissue types can be combined in multiple bioreactors. The activities of multiple bioreactors can be coordinated and controlled in an automated manner by a supervisor controller. The supervisor controller can receive user input at the start of the process, and can manage the process henceforth, alerting the user if user actions are required.


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