The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2023
Filed:
Jul. 03, 2018
Applicant:
The Board of Regents of the University of Texas System, Austin, TX (US);
Inventors:
Andre F. Martins, Plano, TX (US);
Sara Chirayil, Plano, TX (US);
Maria Veronica Clavijo Jordan, Dallas, TX (US);
A. Dean Sherry, Dallas, TX (US);
Assignee:
The Board of Regents of The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 49/10 (2006.01); A61B 5/00 (2006.01); C07F 5/00 (2006.01); G01R 33/56 (2006.01); A61B 5/055 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61B 5/004 (2013.01); A61B 5/055 (2013.01); A61B 5/425 (2013.01); A61B 5/4381 (2013.01); A61K 49/106 (2013.01); C07F 5/003 (2013.01); G01R 33/5601 (2013.01);
Abstract
In some aspects, the present disclosure provides gadolinium based sensors which may be used to image zinc ions in vivo. In some embodiments, the compounds show appropriate reactivity with zinc ions while maintaining high relaxivity to achieve improved background relative to other sensors.