The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2023
Filed:
Jul. 31, 2017
Pfizer Inc., New York, NY (US);
Russell George Dushin, Old Lyme, CT (US);
Daniel P. Uccello, Colchester, CT (US);
Jeremy Starr, Mystic, CT (US);
Ye Che, Niantic, CT (US);
Mark Flanagan, Gales Ferry, CT (US);
Jeffrey M. Casavant, Franklin, CT (US);
Christopher John O'Donnell, Mystic, CT (US);
Gary Frederick Filzen, Schwenksville, PA (US);
Jennifer Young, Groton, CT (US);
Joseph A. Abramite, San Diego, CA (US);
Lawrence N. Tumey, Pawcatuck, CT (US);
Ludivine Moine, Uncasville, CT (US);
Adam Matthew Gilbert, Guilford, CT (US);
Lee R. Roberts, Cambridge, MA (US);
Pfizer Inc., New York, NY (US);
Abstract
The present invention is directed to novel heteroaryl sulfone-based conjugation handles of the formula: (wherein R, R, Het, D, E, X, Y, Z, m, n, p, q, r, s and t are as defined herein), methods for their preparation, their use in synthesizing antibody drug conjugates, and the resulting antibody drug conjugates made with components having heteroaryl sulfone-based conjugation handles.