The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2023
Filed:
Oct. 17, 2018
Applicant:
The Jackson Laboratory, Bar Harbor, ME (US);
Inventors:
David V. Serreze, Bar Harbor, ME (US);
Jeremy J. Racine, Bar Harbor, ME (US);
Assignee:
The Jackson Laboratory, Bar Harbor, ME (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); A61K 49/00 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0276 (2013.01); A61K 49/0008 (2013.01); C12N 15/8509 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0325 (2013.01); A01K 2267/0362 (2013.01); A01K 2267/0387 (2013.01); C12N 2015/8563 (2013.01);
Abstract
The present disclosure relates to genetically modified non-obese diabetic (NOD) mice deficient in murine class I MHC molecules, class II molecules, or both class I and class II MHC molecules. The MHC knockout transgenic mice provided herein are useful, for example, for developing therapies for diabetes.