The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2023
Filed:
Sep. 17, 2018
Waters Technologies Corporation, Milford, MA (US);
Matthew A. Lauber, North Smithfield, RI (US);
Mathew H. DeLano, Needham, MA (US);
Scott A. McCall, Smithfield, RI (US);
Jonathan L. Belanger, Whitinsville, MA (US);
Theodore A. Dourdeville, Falmouth, MA (US);
Kerri M. Smith, Marlborough, MA (US);
Paul D. Rainville, Princeton, MA (US);
Dimple D. Shah, Medway, MA (US);
Stephen J. Shiner, Holden, MA (US);
Catalin Doneanu, Franklin, MA (US);
Michael Donegan, Charlton, MA (US);
Waters Technologies Corporation, Milford, MA (US);
Abstract
A device for separating analytes is disclosed. The device has a sample injector, sample injection needle, sample reservoir container in communication with the sample injector, chromatography column downstream of the sample injector, and fluid conduits connecting the sample injector and the column. The interior surfaces of the fluid conduits, sample injector, sample reservoir container, and column form a flow path having wetted surfaces. A portion of the wetted surfaces of the flow path are coated with an alkylsilyl coating that is inert to at least one of the analytes. The alkylsilyl coating has the Formula I: R, R, R, R, R, and Rare each independently selected from (C-C)alkoxy, —NH(C-C)alkyl, —N((C-C)alkyl), OH, OR, and halo. Rrepresents a point of attachment to the interior surfaces of the fluidic system. At least one of R, R, R, R, R, and Ris OR. X is (C-C)alkyl, —O[(CH)O]—, —(C-C)[NH(CO)NH(C-C)]—, or —(C-C)[alkylphenyl(C-C)alkyl]-.