The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2023
Filed:
Nov. 16, 2018
American Molecular Laboratories Inc., Vernon Hills, IL (US);
Hongjun Zhang, Vernon Hills, IL (US);
Yi Zhou, Vernon Hills, IL (US);
Rajarao Kakuturu, Vernon Hills, IL (US);
AMERICAN MOLECULAR LABORATORIES INC., Vernon Hills, IL (US);
Abstract
The present disclosure provides methods and materials for determining if antibiotic resistantis present in a sample. The methods may comprise obtaining a threshold level ofDNA from the sample, amplifying a region of theDNA to generate multiple copies of the region of theDNA, sequencing the multiple copies of the region of theDNA, comparing sequences of multiple copies of the region of theDNA to a reference sequence, identifying the presence of a mutation in multiple copies of the region of theDNA, and determining a number of the multiple copies of the region of theDNA with the mutation, wherein antibiotic resistantis present in the sample when the number of the multiple copies of the region of theDNA with the mutation is above a predetermined amount.