The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2023
Filed:
Feb. 26, 2021
Celera Corporation, San Juan Capistrano, CA (US);
Bristol-myers Squibb Company, Princeton, NJ (US);
Olga Iakoubova, San Ramon, CA (US);
James J. Devlin, Lafayette, CA (US);
Zenta Tsuchihashi, Skillman, NJ (US);
Peter Shaw, Yardley, PA (US);
Lynn Marie Ploughman, Washington Crossing, PA (US);
Kim E. Zerba, New Hope, PA (US);
Koustubh Ranade, Princeton, IN (US);
Todd Kirchgessner, North Whales, PA (US);
Celera Corporation, San Juan Capistrano, CA (US);
Abstract
The present invention is based on the discovery of genetic polymorphisms that are associated with cardiovascular disorders, particularly acute coronary events such as myocardial infarction and stroke, and genetic polymorphisms that are associated with responsiveness of an individual to treatment of cardiovascular disorders with statin. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.