The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2023

Filed:

Jun. 05, 2020
Applicant:

Genomatica, Inc., San Diego, CA (US);

Inventors:

Anthony P. Burgard, Elizabeth, PA (US);

Mark J. Burk, San Diego, CA (US);

Robin E. Osterhout, San Diego, CA (US);

Jun Sun, San Diego, CA (US);

Priti Pharkya, San Diego, CA (US);

Assignee:

Genomatica Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/18 (2006.01); C12N 15/52 (2006.01);
U.S. Cl.
CPC ...
C12P 7/18 (2013.01); C12N 15/52 (2013.01);
Abstract

Provided herein is a non-naturally occurring microbial organism having a 1,3-butanediol (1,3-BDO) pathway and comprising at least one exogenous nucleic acid encoding a 1,3-BDO pathway enzyme expressed in a sufficient amount to produce 1,3-BDO. In some embodiments, the pathway includes reducing equivalents from CO or hydrogen. In certain embodiments, a 1,3-BDO pathway proceeds by way of central metabolites pyruvate, succinate or alpha-ketoglutarate. Also provided herein is a method for producing 1,3-BDO, includes culturing such microbial organisms under conditions and for a sufficient period of time to produce 1,3-BDO.


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