The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2023

Filed:

Jun. 26, 2020
Applicant:

Factor Bioscience Inc., Cambridge, MA (US);

Inventors:

Matthew Angel, Cambridge, MA (US);

Christopher Rohde, Cambridge, MA (US);

Assignee:

Factor Bioscience Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12N 15/87 (2006.01); C08K 5/5399 (2006.01); C12N 5/074 (2010.01); H01L 31/048 (2014.01); C12P 21/00 (2006.01); C12N 9/16 (2006.01); C12N 5/0789 (2010.01); C12N 5/077 (2010.01); C12N 15/90 (2006.01); C12N 9/22 (2006.01); A61K 35/28 (2015.01); C08G 77/08 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 15/87 (2013.01); A61K 35/28 (2013.01); C08K 5/5399 (2013.01); C12N 5/0647 (2013.01); C12N 5/0657 (2013.01); C12N 5/0696 (2013.01); C12N 9/16 (2013.01); C12N 9/22 (2013.01); C12N 15/907 (2013.01); C12P 21/00 (2013.01); C12Y 301/21 (2013.01); H01L 31/048 (2013.01); A61K 2035/124 (2013.01); C08G 77/08 (2013.01); C12N 2500/25 (2013.01); C12N 2500/44 (2013.01); C12N 2501/115 (2013.01); C12N 2501/155 (2013.01); C12N 2501/165 (2013.01); C12N 2501/2303 (2013.01); C12N 2501/26 (2013.01); C12N 2501/91 (2013.01); C12N 2501/998 (2013.01); C12N 2506/09 (2013.01); C12N 2800/80 (2013.01); Y02E 10/50 (2013.01);
Abstract

The present invention relates in part to nucleic acids encoding proteins, nucleic acids containing non-canonical nucleotides, therapeutics comprising nucleic acids, methods, kits, and devices for inducing cells to express proteins, methods, kits, and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods for inducing cells to express proteins and for reprogramming and gene-editing cells using RNA are disclosed. Methods for producing cells from patient samples, cells produced using these methods, and therapeutics comprising cells produced using these methods are also disclosed.


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