The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2023

Filed:

Jun. 09, 2017
Applicant:

Myriad Women's Health, Inc., South San Francisco, CA (US);

Inventors:

Eric Andrew Evans, Brisbane, CA (US);

Imran Saeedul Haque, San Francisco, CA (US);

Kyle Beauchamp, San Francisco, CA (US);

Clement Chu, South San Francisco, CA (US);

Carlo G. Artieri, San Bruno, CA (US);

Noah Welker, Half Moon Bay, CA (US);

Assignee:

Myriad Women's Health, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12Q 1/6869 (2018.01); C12Q 1/6806 (2018.01); C12N 9/12 (2006.01); C12Q 1/6832 (2018.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1093 (2013.01); C12N 9/1252 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6832 (2013.01); C12Q 1/6869 (2013.01); C12N 15/10 (2013.01); C12P 19/34 (2013.01); C12Q 2525/191 (2013.01); C12Q 2527/107 (2013.01); C12Q 2563/179 (2013.01); C12Y 207/07007 (2013.01);
Abstract

High-fidelity, high-throughput nucleic acid sequencing enables healthcare practitioners and patients to gain insight into genetic variants and potential health risks. However, previous methods of nucleic acid sequencing often introduces sequencing errors (for example, mutations that arise during the preparation of a nucleic acid library, during amplification, or sequencing). Provided herein are sequencing adapters comprising a nondegenerate or variable length molecular barcode and compositions comprising a plurality of sequencing adapters, which can be useful for sequencing nucleic acids. Further provided are methods of using the sequencing adapters, including methods of sequencing nucleic acids, methods of identifying an error in a nucleic acid sequence, and methods of determining the number of nucleic acid molecules in a library.


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