The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2023
Filed:
Oct. 29, 2018
Applicants:
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
New York Blood Center, Inc., New York, NY (US);
Inventors:
Stella Chou, Bryn Mawr, PA (US);
Connie Westhoff, New York, NY (US);
Assignees:
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
New York Blood Center, Inc., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 39/145 (2006.01); C12N 7/00 (2006.01); A61K 35/17 (2015.01); C12N 5/078 (2010.01); A61K 35/14 (2015.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); G01N 33/68 (2006.01); G01N 33/80 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0634 (2013.01); A61K 35/14 (2013.01); C12N 9/22 (2013.01); C12N 15/111 (2013.01); G01N 33/6854 (2013.01); C12N 2310/20 (2017.05); C12N 2510/00 (2013.01); G01N 33/80 (2013.01);
Abstract
Provided herein are engineered red blood cells expressing rare blood antigen group profiles, and methods of making use the same, are described. Also provided are recombinant reagent red blood cells that express or lack the expression of at least one protein (e.g., a blood group antigen) on its surface and uses thereof.