The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2023
Filed:
Oct. 11, 2019
Applicant:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Inventors:
Shannon Bruse, Tarrytown, NY (US);
Shane McCarthy, Tarrytown, NY (US);
Aris Baras, Tarrytown, NY (US);
Frederick Dewey, Tarrytown, NY (US);
Omri Gottesman, Tarrytown, NY (US);
Assignee:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/28 (2006.01); A61P 11/06 (2006.01); A61P 11/00 (2006.01); C12Q 1/6883 (2018.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2866 (2013.01); A61P 11/00 (2018.01); A61P 11/06 (2018.01); C12Q 1/6883 (2013.01); A61K 2039/507 (2013.01); C07K 16/244 (2013.01); C07K 2317/76 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/156 (2013.01);
Abstract
IL33 antagonists alone or in combination with IL-4R antagonists can be used to treat or inhibit eosinophilic asthma, eosinophilic COPD, eosinophilic ACOS, and nasal polyps in a subject having one or more risk alleles in the intronic IL1RL1 variant rs1420101, in the IL33 variant rs1342326, in both, or in variants in linkage disequilibrium thereof.