The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2023
Filed:
Apr. 07, 2021
Applicant:
Case Western Reserve University, Cleveland, OH (US);
Inventors:
James P. Basilion, Shaker Heights, OH (US);
Richard Agnes, Cleveland, OH (US);
Assignee:
CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); C07K 7/56 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); C07K 7/56 (2013.01);
Abstract
A probe for imaging EGFR expressing cells includes an EGFR targeting moiety, a reporter moiety, and a hydrophilic linker that links the EGFR targeting moiety to the reporter moiety. The hydrophilic linker enhances solubility of the probe in an aqueous media as well as binding affinity of the probe to EGFR expressing cells.