The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2023
Filed:
Jun. 10, 2019
The General Hospital Corporation, Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Ralph Mazitschek, Belmont, MA (US);
Sofia A. Santos, Saugus, MA (US);
Mark A. Tye, San Ramon, CA (US);
N. Connor Payne, Cambridge, MA (US);
Dyann F. Wirth, Boston, MA (US);
The General Hospital Corporation, Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
The present application provides compounds, such as compounds of Formula Ia, which are inhibitors of aminoacyl tRNA-synthetase (e.g., prolyl-tRNA-synthetase), and which are useful for treating disorders associated with aminoacyl tRNA-synthetase activity and/or expression. Pharmaceutical compositions comprising the compounds and methods of using the compounds are also provided.