The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2023
Filed:
Aug. 03, 2017
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Matthew Beaver, Natick, MA (US);
Sheng Cui, Lexington, MA (US);
Xiangqing Shi, Newbury Park, CA (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 301/12 (2006.01); B01J 31/16 (2006.01); C07D 303/36 (2006.01);
U.S. Cl.
CPC ...
C07D 301/12 (2013.01); B01J 31/1616 (2013.01); B01J 2531/72 (2013.01); C07D 303/36 (2013.01);
Abstract
The present invention provides new methods for preparing compound 5, and pharmaceutically acceptable salts thereof, of structure Compound 5, or a pharmaceutically acceptable salt thereof, is an important intermediate in the synthesis of carfilzomib. The invention further provides methods of making a useful manganese catalyst that may be used in the epoxidation step of the present invention.