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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11708326 B1

PDFFull Text
Date of Patent:
Jul. 25, 2023

Filed:

Nov. 30, 2020

Immunomodulator compounds

Applicant:

Chemocentryx, Inc., Mountain View, CA (US);

Inventors:

Christopher Lange, Hayward, CA (US);

Viengkham Malathong, Mountain View, CA (US);

Venkat Reddy Mali, Cupertino, CA (US);

Jeffrey McMahon, San Francisco, CA (US);

Darren J. McMurtrie, Sunnyvale, CA (US);

Sreenivas Punna, Sunnyvale, CA (US);

Howard S. Roth, Sunnyvale, CA (US);

Rajinder Singh, Belmont, CA (US);

Yu Wang, Palo Alto, CA (US);

Ju Yang, Palo Alto, CA (US);

Penglie Zhang, Foster City, CA (US);

Assignee:

CHEMOCENTRYX, INC., Thousand Oaks, CA (US);

Attorney:

Amy C. Madl

Primary Examiner:

Craig D Ricci

Int. Cl.
CPC ...
C07D 207/12 (2006.01); A61K 45/06 (2006.01); C07D 401/12 (2006.01); C07D 207/267 (2006.01); C07D 211/44 (2006.01); C07D 403/12 (2006.01); C07D 211/38 (2006.01); C07D 451/06 (2006.01); C07D 205/12 (2006.01); C07F 5/02 (2006.01); C07D 405/14 (2006.01); C07D 401/14 (2006.01); C07D 471/10 (2006.01); C07D 211/76 (2006.01); A61P 37/02 (2006.01); C07D 205/04 (2006.01); C07D 213/85 (2006.01); C07D 295/088 (2006.01); C07D 487/10 (2006.01); C07D 405/12 (2006.01); A61K 31/40 (2006.01); A61K 31/4427 (2006.01); A61K 31/445 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); C07D 211/40 (2006.01); C07D 211/46 (2006.01);
U.S. Cl.
CPC ...
C07D 207/12 (2013.01); A61K 31/40 (2013.01); A61K 31/445 (2013.01); A61K 31/4427 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 45/06 (2013.01); A61P 37/02 (2018.01); C07D 205/04 (2013.01); C07D 205/12 (2013.01); C07D 207/267 (2013.01); C07D 211/38 (2013.01); C07D 211/40 (2013.01); C07D 211/44 (2013.01); C07D 211/46 (2013.01); C07D 211/76 (2013.01); C07D 213/85 (2013.01); C07D 295/088 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 451/06 (2013.01); C07D 471/10 (2013.01); C07D 487/10 (2013.01); C07F 5/025 (2013.01);
Abstract

Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein Z, L, R, R, R, R, R, R, R, R, R, R, R, R, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

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