The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2023
Filed:
Mar. 10, 2021
Applicant:
The United States of America, As Represented BY the Secretary, Department of Health and Human Service, Bethesda, MD (US);
Inventors:
Martin J. Schnermann, Rockville, MD (US);
Megan S. Michie, Frederick, MD (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); C07D 491/147 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0032 (2013.01); C07D 491/147 (2013.01); A61K 2123/00 (2013.01);
Abstract
Conformationally restricted cyanine fluorophores, as well as methods of making and using the compounds, are described. The conformationally restricted cyanine fluorophores have a chemical structure according to Formula I, or a stereoisomer or pharmaceutically acceptable salt thereof: wherein A is and wherein each '*' designates an attachment point of A.