The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2023

Filed:

Apr. 20, 2020
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Jianxin Gu, Paramus, NJ (US);

Rajesh Kumar Kainthan, Tappan, NY (US);

Jin-Hwan Kim, Suffern, NY (US);

Avvari Krishna Prasad, Chapel Hill, NC (US);

Yu-Ying Yang, Stamford, CT (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/107 (2006.01); A61K 47/64 (2017.01); A61K 39/09 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6415 (2017.08); A61K 39/092 (2013.01); A61K 47/646 (2017.08); A61K 2039/6037 (2013.01); A61K 2039/627 (2013.01); C07K 1/1077 (2013.01);
Abstract

The present invention relates generally to glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a spacer containing ((2-oxoethyl)thio)). In an aspect the invention provides oxo-eT linked glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a ((2-oxoethyl)thio) spacer having the formula (I): The invention further relates to immunogenic compositions comprising such glycoconjugates, and to methods for the preparation and use of such glycoconjugates and immunogenic compositions.


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