The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2023

Filed:

Feb. 26, 2018
Applicants:

Kunshan Xinyunda Biotech Co., Ltd., Jiangsu, CN;

Kunshan Xinyunda Biotech Co., Ltd. Beijing Branch, Beijing, CN;

Inventors:

Xiyun Yan, Beijing, CN;

Kelong Fan, Beijing, CN;

Meng Zhou, Beijing, CN;

Xuehui Chen, Beijing, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/42 (2017.01); A61P 35/00 (2006.01); A61K 31/704 (2006.01); A61K 45/06 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
A61K 47/42 (2013.01); A61K 31/704 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 14/47 (2013.01);
Abstract

A nanoscale drug carrier capable of crossing the blood-brain barrier. Said carrier can target brain lesions (brain tumors or other neurodegenerative diseases). The targeting drug carrier capable of crossing the blood-brain barrier comprises all-heavy-chain human ferritin or a functional fragments reconstituted structure or a mutant thereof. The manner for crossing the blood-brain barrier of the drug carrier is receptor-mediated transcytosis. The drug carrier provides an effective nanoscale drug carrier for the treatment of brain tumors or other neurodegenerative diseases.


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