The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2023

Filed:

Jan. 11, 2022
Applicants:

Niren Murthy, Atlanta, GA (US);

Christopher Hermann, Atlanta, GA (US);

David Scott Wilson, Atlanta, GA (US);

Xinghai Ning, Atlanta, GA (US);

Barbara D. Boyan, Atlanta, GA (US);

Zvi Schwartz, Atlanta, GA (US);

Robert Guldberg, Marietta, GA (US);

Tamim Diab, Atlanta, GA (US);

Inventors:

Niren Murthy, Atlanta, GA (US);

Christopher Hermann, Atlanta, GA (US);

David Scott Wilson, Atlanta, GA (US);

Xinghai Ning, Atlanta, GA (US);

Barbara D. Boyan, Atlanta, GA (US);

Zvi Schwartz, Atlanta, GA (US);

Robert Guldberg, Marietta, GA (US);

Tamim Diab, Atlanta, GA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/32 (2006.01); A61L 27/52 (2006.01); A61K 9/06 (2006.01); A61K 38/17 (2006.01); C07K 14/51 (2006.01);
U.S. Cl.
CPC ...
A61K 47/32 (2013.01); A61K 9/06 (2013.01); A61K 38/1709 (2013.01); A61L 27/52 (2013.01); C07K 14/51 (2013.01); A61L 2430/02 (2013.01);
Abstract

Compositions and methods are described for a polymer hydrogel created by a cycloaddition reaction between an azide and an alkyne that proceeds rapidly without catalyst to produce the polymer hydrogel in less than ninety seconds. The polymer hydrogel can be used in in vivo applications for the localized delivery of therapeutic agent in aqueous solutions. An example of therapeutic delivery of a protein in a mouse model is demonstrated.


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