The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2023

Filed:

Sep. 23, 2016
Applicants:

The General Hospital Corporation, Boston, MA (US);

Rhode Island Hospital, a Lifespan-partner, Providence, RI (US);

Inventors:

Helen Burgwyn Fuchs, Quincy, MA (US);

Eleftherios Mylonakis, Providence, RI (US);

Frederick M. Ausubel, Newton, MA (US);

Raj Mohan Raja Muthiah, San Jose, CA (US);

Wooseong Kim, Providence, RI (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/192 (2006.01); A61K 31/7036 (2006.01); A61P 31/04 (2006.01); A61K 38/17 (2006.01); A61K 45/06 (2006.01); A61P 31/10 (2006.01); A61K 9/00 (2006.01); A61K 31/4196 (2006.01); A61K 31/5383 (2006.01); A61K 31/7048 (2006.01); A61K 31/7135 (2006.01);
U.S. Cl.
CPC ...
A61K 31/192 (2013.01); A61K 9/0014 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 31/4196 (2013.01); A61K 31/5383 (2013.01); A61K 31/7036 (2013.01); A61K 31/7048 (2013.01); A61K 31/7135 (2013.01); A61K 38/1729 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01); A61P 31/10 (2018.01); Y02A 50/30 (2018.01);
Abstract

The present application provides that synthetic retinoid compounds are useful in methods of treating bacterial infections, such as a bacterial infection caused by, methicillin-resistant(MRSA), vancomycin-resistant(VRSA),, and. The present application also provides a tricyclic fluoroquinolone compound, Z3060, useful in methods of treating bacterial infections, such as a bacterial infection caused by, methicillin-resistant(MRSA), vancomycin-resistant(VRSA),. spp.,, and. Also provided herein is a gold compound, auranofin, useful in treating bacterial and fungal infections, such as a fungal infection caused by, and


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