The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2023

Filed:

Dec. 18, 2018
Applicant:

Janssen Pharmaceuticals, Inc., Titusville, NJ (US);

Inventors:

Wayne Drevets, San Diego, CA (US);

Honglan Li, Pennington, NJ (US);

David Wood Hough, Pennington, NJ (US);

Jaskaran Singh, San Diego, CA (US);

Ewa Wajs, Beerse, BE;

Assignee:

Janssen Pharmaceuticals, Inc., Titusville, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/135 (2006.01); A61P 25/24 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/135 (2013.01); A61K 9/0043 (2013.01); A61K 9/0053 (2013.01); A61P 25/24 (2018.01);
Abstract

The present invention provides methods of maintaining stable remission or stable response achieved by a patient with depression following administration of a therapeutically effective amount of esketamine during an initial administration phase, comprising continuing administration of a therapeutically effective amount of esketamine for at least five months during a subsequent administration phase. The present invention also provides methods for the long term treatment of depression in a patient, comprising administering to the patient in need of the treatment a clinically proven safe and clinically proven effective therapeutically effective amount of esketamine for at least six months. In some embodiments, the depression is major depressive disorder or treatment resistant depression.


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