The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2023

Filed:

Aug. 13, 2020
Applicant:

Schott Pharma Ag & Co. Kgaa, Mainz, DE;

Inventors:

Robert Frost, Eggersriet, CH;

Uwe Rothhaar, Birkenheide, DE;

Florence Buscke, Mainz, DE;

Bernhard Hladik, Alzey, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B65D 1/02 (2006.01); C03C 17/30 (2006.01); A61J 1/14 (2023.01); A61J 1/06 (2006.01); C03B 9/335 (2006.01); C03C 3/089 (2006.01);
U.S. Cl.
CPC ...
A61J 1/1468 (2015.05); A61J 1/065 (2013.01); C03B 9/335 (2013.01); C03C 3/089 (2013.01);
Abstract

A glass vial includes a base including a boron-containing multicomponent glass and a vial opening and holds a liquid active pharmaceutical ingredient formulation. The glass vial has a total volume of <4.5 mL. A filling level of the glass vial with the active pharmaceutical ingredient formulation is not more than 0.25 and a concentration of boron ions, measured at a measurement site below a plane of a middle of the glass vial using a concentration depth profile at a depth in a range from 10 to 30 nm, has a value, averaged over the measurements of the concentration depth profile, that has an excess increase of not more than 30% compared to a concentration of boron ions measured using a concentration depth profile at a depth in a range from 10 to 30 nm with a measurement site in the plane of the middle of the glass vial.


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