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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11705220 B1

PDFFull Text
Date of Patent:
Jul. 18, 2023

Filed:

Apr. 22, 2021

Systems and methods for identifying cancer treatments from normalized biomarker scores

Applicant:

Bostongene Corporation, Waltham, MA (US);

Inventors:

Alexander Bagaev, Moscow, RU;

Feliks Frenkel, Moscow, RU;

Ravshan Ataullakhanov, Moscow, RU;

Assignee:

BostonGene Corporation, Waltham, MA (US);

Attorney:

Wolf, Greenfield & Sacks, P.C.

Primary Examiner:

G Steven Vanni

Int. Cl.
CPC ...
G16B 45/00 (2019.01); G16H 50/30 (2018.01); C12Q 1/6886 (2018.01); G16H 50/20 (2018.01); G16H 50/70 (2018.01); G06F 16/28 (2019.01); G16B 5/00 (2019.01); G16B 20/00 (2019.01); G16B 40/00 (2019.01); G16B 50/00 (2019.01); G16B 5/20 (2019.01); G16B 25/10 (2019.01); G16B 40/20 (2019.01); G16B 50/30 (2019.01); G16B 40/30 (2019.01); G16B 30/00 (2019.01); G06F 17/18 (2006.01); G16H 20/00 (2018.01); G16H 50/50 (2018.01); G16H 20/10 (2018.01); G16H 20/40 (2018.01); G16H 70/20 (2018.01); G16H 10/20 (2018.01);
U.S. Cl.
CPC ...
G16B 45/00 (2019.02); C12Q 1/6886 (2013.01); G06F 16/285 (2019.01); G06F 17/18 (2013.01); G16B 5/00 (2019.02); G16B 5/20 (2019.02); G16B 20/00 (2019.02); G16B 25/10 (2019.02); G16B 30/00 (2019.02); G16B 40/00 (2019.02); G16B 40/20 (2019.02); G16B 40/30 (2019.02); G16B 50/00 (2019.02); G16B 50/30 (2019.02); G16H 10/20 (2018.01); G16H 20/00 (2018.01); G16H 20/10 (2018.01); G16H 20/40 (2018.01); G16H 50/20 (2018.01); G16H 50/30 (2018.01); G16H 50/50 (2018.01); G16H 50/70 (2018.01); G16H 70/20 (2018.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01);
Abstract

Techniques for generating therapy biomarker scores and visualizing same. The techniques include determining, using a patient's sequence data and distributions of biomarker values across one or more reference populations, a first set of normalized scores for a first set of biomarkers associated with a first therapy, and a second set of normalized scores for a second set of biomarkers associated with a second therapy, generating a graphical user interface (GUI) including a first portion associated with the first therapy and having at least one visual characteristic determined based on a normalized score of the respective biomarker in the first set of normalized scores; and a second portion associated with a second therapy and having at least one visual characteristic determined based on a normalized score of the respective biomarker in the second set of normalized scores; and displaying the generated GUI.

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