The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2023

Filed:

Feb. 08, 2018
Applicant:

Asymchem Laboratories (Tianjin) Co., Ltd., TEDA Tianjin, CN;

Inventors:

Hao Hong, Morrisville, NC (US);

James Gage, Morrisville, NC (US);

Jiangping Lu, Tianjin, CN;

Xuecheng Jiao, Tianjin, CN;

Na Zhang, Tianjin, CN;

Rui Li, Tianjin, CN;

Kejian Zhang, Tianjin, CN;

Yu Zhang, Tianjin, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2006.01); C12N 15/53 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0073 (2013.01); C12Y 114/13022 (2013.01);
Abstract

The present application relates to the technical field of genetic engineering, and provides a monooxygenase mutant, a preparation method and application thereof. The monooxygenase mutant has any one of the amino acid sequences shown in (I) and (II): (I) an amino acid sequence having at least 80% identity with the amino acid sequence shown in SEQ ID NO. 1; and (II) an amino acid sequence obtained by modifying, substituting, deleting, or adding one or several amino acids to the amino acids at 23 to 508 positions of the amino acid sequence shown in SEQ ID NO. 1, the substituting referring to a substitution of 1 to 34 amino acids, wherein the mutant has the activity of monooxygenase.


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