The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2023
Filed:
May. 11, 2018
Applicant:
University of Massachusetts, Boston, MA (US);
Inventors:
Gregory N. Tew, South Deerfield, MA (US);
Lisa M. Minter, Southampton, MA (US);
Emrah Ilker Ozay, Amherst, MA (US);
Assignee:
University of Massachusetts, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C07K 16/40 (2006.01); C08G 61/12 (2006.01); C12N 5/0783 (2010.01); A61K 35/17 (2015.01); A61K 38/00 (2006.01); A61K 45/06 (2006.01); A61K 47/32 (2006.01); C07K 16/18 (2006.01); C12N 9/10 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0636 (2013.01); C07K 16/40 (2013.01); A61K 35/17 (2013.01); A61K 38/00 (2013.01); A61K 45/06 (2013.01); A61K 47/32 (2013.01); C07K 16/18 (2013.01); C07K 2317/24 (2013.01); C08G 61/12 (2013.01); C08G 2261/3242 (2013.01); C08G 2261/3342 (2013.01); C12N 9/1007 (2013.01); C12N 9/12 (2013.01); C12Y 201/01077 (2013.01); C12Y 207/11013 (2013.01);
Abstract
The disclosure provides an ex vivo method to prepare regulatory T cells, a population of regulatory T cells with enhanced properties and methods of using the population or complexes useful to induce Tregs in a mammal. The ex vivo methods allows for the generation and expansion of super regulatory T cells for the prevention, inhibition or treatment of autoimmune disorders.