The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2023
Filed:
Nov. 17, 2017
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Bin Liu, San Francisco, CA (US);
Namkyung Lee, San Francisco, CA (US);
Yang Su, San Francisco, CA (US);
Scott Bidlingmaier, San Francisco, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); C07K 16/28 (2006.01); A61K 31/713 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 31/713 (2013.01); C07K 16/2821 (2013.01); C07K 16/2866 (2013.01); C07K 16/468 (2013.01); C07K 2317/31 (2013.01); C07K 2317/622 (2013.01); C07K 2317/64 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present disclosure relates to an engineered antibody that co-engages a cell type-selective (or specific) antigen (guide) and a signaling receptor (effector) on a target cell. In some instances, the engineered antibody is capable of modulating a signaling pathway on a target cell. In other embodiments, an engineered antibody of the present disclosure is administered to a subject for the treatment of a disease or condition.