The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2023
Filed:
Aug. 28, 2019
Applicant:
Ucb Pharma, S.a., Brussels, BE;
Inventors:
Assignee:
UCB Pharma, S.A., Brussels, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 33/50 (2006.01); G01N 33/577 (2006.01); C07K 16/22 (2006.01); C07K 14/51 (2006.01); C07K 16/18 (2006.01); A61K 47/64 (2017.01); C07K 14/475 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 47/643 (2017.08); A61K 47/646 (2017.08); C07K 14/475 (2013.01); C07K 14/51 (2013.01); C07K 16/18 (2013.01); G01N 33/6854 (2013.01); C07K 2317/76 (2013.01); G01N 33/50 (2013.01); G01N 33/577 (2013.01); G01N 33/68 (2013.01); G01N 33/6863 (2013.01); G01N 2333/4704 (2013.01);
Abstract
Compositions and methods relating to antibodies that specifically bind to TGF-beta binding proteins are provided. These methods and compositions relate to altering bone mineral density by interfering with the interaction between a TGF-beta binding protein sclerostin and a TGF-beta superfamily member, particularly a bone morphogenic protein. Increasing bone mineral density has uses in diseases and conditions in which low bone mineral density typifies the condition, such as osteopenia, osteoporosis, and bone fractures.