The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2023

Filed:

Apr. 26, 2019
Applicants:

Sumitomo Pharma Co., Ltd., Osaka, JP;

The Kitasato Institute, Minato-ku, JP;

Inventors:

Toshio Kanai, Osaka, JP;

Sachiko Koike, Osaka, JP;

Takayuki Fukaya, Osaka, JP;

Shunichiro Uesugi, Osaka, JP;

Shingo Mizushima, Osaka, JP;

Hitoshi Suda, Osaka, JP;

Yuki Mizukami, Osaka, JP;

Yohei Ikuma, Osaka, JP;

Toshiaki Sunazuka, Minato-ku, JP;

Yoshihiko Noguchi, Minato-ku, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01); A61P 31/04 (2006.01); A61K 45/06 (2006.01); A61K 31/407 (2006.01); A61K 31/69 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); A61K 31/407 (2013.01); A61K 31/69 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01);
Abstract

Provided is a novel compound that has an excellent β-lactamase inhibitory effect. More specifically, provided is a compound represented by formula (1a), (1b) or (11) having an excellent β-lactamase inhibitory effect or a pharmaceutically acceptable salt thereof. By using this compound either in combination with a β-lactam drug or alone, a useful preventive or therapeutic agent for bacterial infections is provided. Also provided are useful preventive or therapeutic agents for treating various diseases with the combined use of the aforesaid compound and β-lactam drugs.


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