The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2023

Filed:

Feb. 15, 2018
Applicant:

Trevena, Inc., Chesterbrook, PA (US);

Inventors:

Aimee Crombie Speerschneider, Chesterbrook, PA (US);

Dennis Shinji Yamashita, Chesterbrook, PA (US);

Philip Michael Pitis, Chesterbrook, PA (US);

Michael John Hawkins, Chesterbrook, PA (US);

Guodong Liu, Chesterbrook, PA (US);

Tamara Ann Miskowski Daubert, Chesterbrook, PA (US);

Catherine C. K. Yuan, Chesterbrook, PA (US);

Robert Borbo Kargbo, Chesterbrook, PA (US);

Robert Jason Herr, Chesterbrook, PA (US);

Donna Romero, Chesterbrook, PA (US);

Assignee:

TREVENA, INC., Chesterbrook, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); C07D 403/14 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); A61P 25/06 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61P 25/06 (2018.01); A61P 25/22 (2018.01); A61P 25/24 (2018.01); A61P 29/00 (2018.01); C07D 403/14 (2013.01);
Abstract

The present embodiments are directed, in part, to 5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, such as those of Formula I, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof for modulating the activity of delta opioid receptor, biased and/or unbiased, and/or methods for treating pain, migraines, headaches, depression, Parkinson's Disease, anxiety, and/or overactive bladder, and other disorders and conditions described herein or any combination thereof.


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