The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2023
Filed:
Jun. 04, 2019
Applicants:
Ohio State Innovation Foundation, Columbus, OH (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Inventors:
Kevin Hodgetts, Boston, MA (US);
Chien-Liang Glenn Lin, Columbus, OH (US);
Assignees:
OHIO STATE INNOVATION FOUNDATION, Columbus, OH (US);
THE BRIGHAM AND WOMAN'S HOSPITAL, INC., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61P 25/28 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); C07D 237/14 (2006.01); C07D 401/04 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61P 25/22 (2018.01); A61P 25/24 (2018.01); A61P 25/28 (2018.01); C07D 237/14 (2013.01); C07D 401/04 (2013.01); C07D 413/14 (2013.01);
Abstract
Disclosed are compounds that activate excitatory amino acid transporter 2 (EAAT2), as well as methods of using these compounds to treat or preventing diseases, disorders, and conditions associated with glutamate excitotoxicity.