The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2023
Filed:
Feb. 22, 2021
Applicant:
Merck Patent Gmbh, Darmstadt, DE;
Inventors:
Catherine Jorand-Lebrun, Billerica, MA (US);
Roch Boivin, Billerica, MA (US);
Theresa Johnson, Billerica, MA (US);
Yanping Wang, Billerica, MA (US);
Yufang Xiao, Billerica, MA (US);
Xiaoling Chen, Billerica, MA (US);
Nina Linde, Darmstadt, DE;
Doreen Musch, Darmstadt, DE;
Deepak Kumar, Billerica, MA (US);
Assignee:
Merck Patent GmbH, Darmstadt, DE;
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/36 (2006.01); C07D 239/42 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 471/10 (2006.01); C07D 487/10 (2006.01); C07D 491/052 (2006.01); C07D 491/107 (2006.01); C07D 491/20 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 239/36 (2013.01); A61P 35/00 (2018.01); C07D 239/42 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 471/10 (2013.01); C07D 487/10 (2013.01); C07D 491/052 (2013.01); C07D 491/107 (2013.01); C07D 491/20 (2013.01);
Abstract
The invention relates to pyrimidinone derivatives of the general Formula I, or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.