The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2023
Filed:
May. 14, 2018
President and Fellows of Harvard College, Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
The General Hospital Corporation, Boston, MA (US);
Denitsa M. Milanova, Boston, MA (US);
George M. Church, Brookline, MA (US);
Noah Davidsohn, Brookline, MA (US);
Carl Schoellhammer, Medford, MA (US);
Robert S. Langer, Newton, MA (US);
Anna I. Mandinova, Newton, MA (US);
Carlo Giovanni Traverso, Newton, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
The General Hospital Corporation, Boston, MA (US);
Abstract
A method for the systemic delivery of a polypeptide within a subject is provided by creating genetically modified skin cells via topical introduction of a genetically engineered virus which delivers a nucleic acid encoding a therapeutic polypeptide for expression by the skin cells, wherein the expressed therapeutic polypeptide is secreted by the skin cells and is introduced into the circulatory system of the subject.