The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2023
Filed:
Jan. 07, 2020
Applicant:
Akamara Therapeutics, Inc., Philadelphia, PA (US);
Inventors:
Shiladitya Sengupta, Waltham, MA (US);
Monideepa Roy, Delhi, IN;
Nimish Gupta, Delhi, IN;
Seikh Samad Hossain, Delhi, IN;
Assignee:
AKAMARA THERAPEUTICS, INC., Philadelphia, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 47/68 (2017.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6851 (2017.08); A61K 47/6803 (2017.08); A61K 47/6849 (2017.08); A61K 47/6889 (2017.08); C07K 16/2863 (2013.01); C07K 16/32 (2013.01); C07K 2317/52 (2013.01); C07K 2317/73 (2013.01);
Abstract
The current invention describes a conjugate of a targeting moiety linked to a drug via a molecule having high affinity for the targeting moiety at physiological pH such that the drug releases at low pH from the targeting moiety.