The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2023

Filed:

Sep. 22, 2021
Applicant:

Grifols Worldwide Operations Limited, Dublin, IE;

Inventors:

James Rebbeor, Garner, NC (US);

Charles Miller, Apex, NC (US);

Anthony Klos, Raleigh, NC (US);

Eric Allgaier, Wake Forest, NC (US);

Thomas P. Zimmerman, Raleigh, NC (US);

Kevin Wee, Wake Forest, NC (US);

Michelle StPeter, Graner, NC (US);

Kelly Glancy, Holly Springs, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/55 (2006.01); A61K 47/12 (2006.01); A61K 47/26 (2006.01); A61K 47/30 (2006.01);
U.S. Cl.
CPC ...
A61K 38/55 (2013.01); A61K 47/12 (2013.01); A61K 47/26 (2013.01); A61K 47/30 (2013.01);
Abstract

Compositions include highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly-concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).


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