The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2023

Filed:

Jun. 23, 2021
Applicant:

University of Louisville Research Foundation, Inc., Louisville, KY (US);

Inventors:

Tongalp H. Tezel, New York, NY (US);

Andrea S. Gobin, Pearland, TX (US);

Martin G. O'Toole, Louisville, KY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C08F 2/46 (2006.01); C08F 2/50 (2006.01); C08G 61/04 (2006.01); A61K 31/7016 (2006.01); C08L 1/28 (2006.01); C08L 5/02 (2006.01); C08L 5/08 (2006.01); C08L 5/10 (2006.01); A61K 9/00 (2006.01); A61K 47/32 (2006.01); A61K 47/38 (2006.01); C08L 33/14 (2006.01); A61F 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7016 (2013.01); A61K 9/0048 (2013.01); A61K 9/0051 (2013.01); A61K 47/32 (2013.01); A61K 47/38 (2013.01); C08L 1/284 (2013.01); C08L 5/02 (2013.01); C08L 5/08 (2013.01); C08L 5/10 (2013.01); C08L 33/14 (2013.01); A61F 9/00 (2013.01); C08L 2205/05 (2013.01);
Abstract

Polymeric compositions are provided that include a poly(ethylene glycol), a viscoelastic polymer, and an antioxidant, where, in polymerized form, the compositions have a refractive index of about 1.30 to about 1.40. Methods of synthesizing the compositions are also provided and include the steps of heating an amount of water; adding a buffering agent to the water to form a buffer solution; mixing a poly(ethylene glycol) and a viscoelastic polymer into the buffer solution to form a reactive mixture; adding a plurality of antioxidant particles to the reactive mixture; and removing suspended gas bubbles from the reactive mixture. Methods of preventing oxidative damage to an eye lens of a subject are further provided and include administering the foregoing polymeric compositions to the eye lens of the subject.


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