The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2023
Filed:
Aug. 07, 2020
Applicant:
Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, CN;
Inventors:
Xiaohui Zhao, Xining, CN;
Ting Zhang, Xining, CN;
Huilan Yue, Xining, CN;
Jihong Tao, Xining, CN;
Wenjing Jia, Xining, CN;
Guoying Zhou, Xining, CN;
Lixin Wei, Xining, CN;
Chen Chen, Xining, CN;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/305 (2006.01); A61K 31/4406 (2006.01); A61K 47/12 (2006.01); A61K 47/26 (2006.01); A61K 47/38 (2006.01); A61K 9/00 (2006.01); A61K 9/14 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
A61K 31/305 (2013.01); A61K 31/4406 (2013.01); A61K 47/12 (2013.01); A61K 47/26 (2013.01); A61K 47/38 (2013.01); A61K 9/0019 (2013.01); A61K 9/14 (2013.01); A61K 9/48 (2013.01);
Abstract
The present invention relates to use of gTso thal in manufacturing a medicament for the promotion of MS-275 to cross the blood-brain barrier (BBB), and belongs to the technical field of pharmaceutical preparation. Administration of the medicament manufactured by the use of the present invention in combination with MS-275 significantly increases MS-275 to cross the BBB into the brain tissue, and prominently promotes the accumulation of MS-275 therein.