The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2023
Filed:
Oct. 29, 2021
Applicant:
Howard Hughes Medical Institute, Chevy Chase, MD (US);
Inventors:
Jonathan S. Marvin, Arlington, VA (US);
Loren Looger, Sterling, VA (US);
Assignee:
Howard Hughes Medical Institute, Chevy Chase, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/557 (2006.01); G01N 33/68 (2006.01); G01N 33/58 (2006.01); C07K 14/195 (2006.01); C07K 14/245 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
G01N 33/557 (2013.01); C07K 14/195 (2013.01); C07K 14/245 (2013.01); C07K 14/43595 (2013.01); G01N 33/582 (2013.01); G01N 33/68 (2013.01); G01N 33/6812 (2013.01); C07K 2319/20 (2013.01); C07K 2319/24 (2013.01); C07K 2319/60 (2013.01); G01N 2400/00 (2013.01); G01N 2458/00 (2013.01);
Abstract
The present disclosure provides, inter alia, genetically encoded recombinant peptide biosensors comprising analyte-binding framework portions and signaling portions, wherein the signaling portions are present within the framework portions at sites or amino acid positions that undergo a conformational change upon interaction of the framework portion with an analyte.