The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2023

Filed:

Jul. 09, 2021
Applicants:

Glaxosmithkline Intellectual Property Development Limited, Middlesex, GB;

Fimbrion Therapeutics, Inc., St. Louis, MO (US);

Inventors:

Michael Joseph Bishop, Research Triangle Park, NC (US);

Eugene L. Stewart, Collegeville, PA (US);

Katherine Louisa Widdowson, San Diego, CA (US);

James Walter Janetka, St. Louis, MO (US);

Laurel Kathryn McGrane, St. Louis, MO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 7/04 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07H 7/04 (2013.01); A61K 9/0014 (2013.01); A61K 9/0053 (2013.01); A61K 9/20 (2013.01); A61K 9/48 (2013.01); A61K 45/06 (2013.01);
Abstract

Disclosed herein are C-mannoside compounds, compositions thereof and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in a human subject are also provided for the treatment of diseases such as bacterial infection, Crohn's disease (CD) and Inflammatory Bowel Disease (IBD).


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