The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2023

Filed:

Nov. 24, 2020
Applicant:

Theravance Biopharma R&d Ip, Llc, South San Francisco, CA (US);

Inventors:

Robert Murray McKinnell, Millbrae, CA (US);

Erik Fenster, San Bruno, CA (US);

Tom M. Lam, San Francisco, CA (US);

Diana Jin Wang, Madison, WI (US);

Anthony Francesco Palermo, Toronto, CA;

Luke Boralsky, San Francisco, CA (US);

Breena Fraga, San Francisco, CA (US);

Assignee:

THERAVANCE BIOPHARMA R&D IP, LLC, South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 45/06 (2013.01);
Abstract

The disclosure provides compounds of formula (I): or a pharmaceutically-acceptable salt thereof, wherein the variables are defined in the specification, that are inhibitors of JAK kinases, particularly JAK3. The disclosure also provides pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat gastrointestinal inflammatory diseases.


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