The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2023

Filed:

Nov. 05, 2021
Applicant:

Eli Lilly and Company, Indianapolis, IN (US);

Inventors:

Gabrielle R. Kolakowski, Longmont, CO (US);

Erin D. Anderson, Boulder, CO (US);

Steven W. Andrews, Longmont, CO (US);

Christopher Pierre Albert Jean Boldron, Toulouse, FR;

Kevin R. Condroski, Lafayette, CO (US);

Thomas C. Irvin, Erie, CO (US);

Manoj Kumar, Broomfield, CO (US);

Elizabeth A. McFaddin, Nederland, CO (US);

Megan L. McKenney, Boulder, CO (US);

Johnathan Alexander McLean, Arvada, CO (US);

Tiphaine Mouret, Toulouse, FR;

Michael J. Munchhof, Corvallis, MT (US);

Thomas Pierre Dino Pancaldi, Toulouse, FR;

Michael Alexander Pilkington-Miksa, Toulouse, FR;

Marta Pinto, Toulouse, FR;

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/12 (2006.01); A61P 35/00 (2006.01); C07D 231/38 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 413/12 (2013.01); A61P 35/00 (2018.01); C07D 231/38 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01);
Abstract

Disclosed herein are compounds of formula I: or a pharmaceutically acceptable salt thereof, where the variables are as defined herein. These compounds are useful in treating RET associated cancers. Formulations containing the compounds of formula I and methods of making the compounds of formula I are also disclosed.


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